Liqui-Care P™ (Pyrantel Pamoate) Equine Anthelmintic Suspension

Liqui-Care P™ (Pyrantel Pamoate) is a suspension of pyrantel pamoate in a palatable vanilla-flavored vehicle. Each mL contains 50 mg of pyrantel base as pyrantel pamoate.

Pyrantel pamoate is a compound belonging to a family classified chemically as tetrahydropyrimidines. It is a yellow, water insoluble crystalline salt of the tetrahydropyrimidine base and pamoic acid containing 34.7% base activity. The chemical structure and name are given below:

(E)-1,4,5,6-Tetrahydro-1-methyl-2- [2-(2-thienyl) vinyl] pyrimidine 4, 4' methylenebis [3-hydroxy-2- naphthoate] (1:1)

INDICATIONS FOR USE
For the removal and control of mature infections of large strongyles ( Strongylus vulgaris, S. edentatus, S. equinus ); pinworms ( Oxyuris equi ); large roundworms ( Parascaris equorum ); and small strongyles in horses and ponies.

DOSAGE AND TREATMENT
Administer 3 mg pyrantel base per pound of body weight (6 mL Liqui-Care P™ (Pyrantel Pamoate) per 100 lb body weight).

For maximum control of parasitism, it is recommended that foals (2-8 months of age) be dosed every 4 weeks. To minimize potential hazard that the mare may pose to the foal, she should be treated 1 month prior to anticipated foaling date followed by retreatment 10 days to 2 weeks after birth of foal. Horses over 8 months of age should be routinely dosed every 6 weeks.

DIRECTIONS FOR USE
Liqui-Care P™ (Pyrantel Pamoate)may be administered by means of a dose syringe or by mixing into the feed.

Dose Syringe - Draw the appropriate dosage of Liqui-Care P™ (Pyrantel Pamoate) into a dose syringe and administer to the animal. Do not expose Liqui-Care P™ (Pyrantel Pamoate) to direct sunlight.

Feed - Mix the appropriate dosage of Liqui-Care P™ (Pyrantel Pamoate) in the normal grain ration. Fasting of animals prior to or following treatment is not required.

CAUTION: THIS PRODUCT IS A SUSPENSION AND AS SUCH WILL SEPARATE. TO INSURE UNIFORM RE-SUSPENSION AND TO ACHIEVE PROPER DOSAGE, IT IS EXTREMELY IMPORTANT THAT THE PRODUCT BE SHAKEN AND STIRRED THOROUGHLY BEFORE EVERY USE.

EFFICACY
Critical (worm-count) studies in horses demonstrated that pyrantel pamoate administered at the recommended dosage was efficacious against mature infections of Strongylus vulgaris (>90%), S. edentatus (69%), S. equinus (>90%), Oxyuris equi (81%), Parascaris equorum (>90%), and small strongyles (>90%).

SAFETY
Pyrantel pamoate is well tolerated by horses and ponies of all ages. No adverse drug response was observed when dose rates up to 60 mg pyrantel base per pound of body weight were administered by stomach tube nor when 3 mg base per pound was given by intratracheal injection. The reproductive performance of pregnant mares and stud horses dosed with pyrantel pamoate has not been affected.

WARNING: NOT FOR HORSES OR PONIES INTENDED FOR FOOD.
KEEP OUT OF REACH OF CHILDREN.

Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism. It is recommended that severely debilitated animals not be treated with this preparation.